Magnesium Absorbency: Our Clinical Trial Results- Thomas DeLauer

Magnesium Absorbency: Our Clinical Trial Results- Thomas DeLauer



magnesium is super super hot right now and I thought I'd do this video to talk about a clinical study that I was actually a part of that had to do with magnesium uptake and magnesium levels in the body so super super proud of this published here in 2018 so brand spanking new but anyway the reason that I want to talk about this is because so many people have been talking about different magnesium products different forms of magnesium and how they absorb in the body and how they're actually utilized so let's get right into what more of the common magnesium's that you would see out on the market are and let's talk about how they act in the body so first of all magnesium can be a little bit sketchy because a lot of times the magnesium ends up not being absorbed very well now if you've ever taken magnesium sulfate which is also known as Epsom salt you know that it actually makes you go to the bathroom quite fast so it causes an osmotic effect within the colon what that means is that it ends up changing up the sku of how water is in the colon versus out of the colon which can throw off mineral balances even more and cause you to have well pretty loose stools and quite honestly feel very very uncomfortable so when you look at a lot of different magnesium products that are out there on the shelves and most stores you're looking at things like magnesium oxide magnesium carbonate and the problem is these have a very low availability within the body which means they end up disturbing that overall osmotic balance that we have in the colon and the small intestine so that bioavailability that is low ends up causing all the GI discomfort that you would ordinarily get with most magnesium so what we did is we wanted to take a look at the different kinds of magnesium and how they're actually absorbed so when you look at what physicians usually recommend for like magnesium deficiency issues and things like that they usually recommend magnesium a lake a magnesium male eight is a lot more expensive but it does have a better bioavailability so what we did is with jigsaw SRT we took a look at something called die magnesium male eight okay so male eight just means that's bound to male ik acid so when you look at die magnesium male eight what we did is we took two magnesium ions and bound them to malic acid so we had a very bioavailable very absorbable form of magnesium then additionally added an SRT component to make it sustain release so that it actually took a longer period of time to absorb so you weren't just getting this massive influx of the body didn't know what to do with so then we get to the study let's talk about what we did in Scott still here that was just published in 2018 so the study was published in the Journal of the American College of nutrition here in 2018 and it's called the Scottsdale magnesium study when we took a look at absorption cellular uptake but also magnesium deficiency symptoms to see if magnesium was truly absorbed and how it affected symptoms based on a questionnaire for participants that started the study was done over a period of 30 to 90 days we took 91 participants so 53 participants that took magnesium SRT from jigsaw okay 500 milligrams and then the rest took a placebo so there's a few things that they wanted to measure her after they took the magnesium supplement they wanted to measure of course their serum magnesium which is the overall levels of magnesium that ultimately ended up in their body then they wanted to look at what's called RBC magnesium okay RBC magnesium stands for red blood cell magnesium this is very very important what this is is this is the magnesium that is actually building up in your body and getting inside your bones okay getting with the red blood cells in the marrow getting into where it needs to go to actually have a long-term effect on the body so we wanted to look at that over a longer period of time serum magnesium can be looked at over a shorter period of time that's more indicative of how well is a product being absorbed or how well is a mineral being absorbed in a shorter amount of time so between four and eight hours after taking the magnesium is when they measured the overall serum magnesium but after 30 and 90 days is when they truly looked at the RBC to see how it was really building up within the body so they found that there was a 22% increase in serum magnesium levels okay this is pretty phenomenal because before now there wasn't any way to really prove whether a magnesium was absorbed or not so when we have a 22% increase in serum magnesium that means that we are literally getting 22 percent more magnesium in our body ready to be used okay now here's where it gets really fascinating there was over a thirty percent increase in RBC magnesium over time again that RBC magnesium is magnesium that's actually getting into the marrow and ultimately being able to be used by the body okay competing against calcium helping your body have a little bit more of a calming effect versus the exit ori effect from excess calcium ions going through the body so a very very powerful that we saw that okay then at the beginning of this study they did give all the participants a questionnaire okay they wanted to note their magnesium deficiency symptoms okay we're talking about things like leg cramps we're talking about things like your inability all these little things that go along with magnesium deficiency then at the end of 30 and 90 days they measured him again they had them fill out another questionnaire and see how their overall symptoms were doing well guess what after 90 days 63 percent decrease in magnesium deficiency symptoms that is powerful so for someone that is normally having leg cramps or someone that is normally having the issues that arise with magnesium deficiency we were able to prove with this Castillo magnesium study that you can start to reduce magnesium deficiency symptoms so if you combine that with a cumulative buildup of magnesium in the body you can start to get the results that you want so hopefully this clears up a little bit about magnesium and how it truly works in the body we're super proud to have published this study super proud to be able to be a part of true science and actually changing lives and I also want to add that ninety-one percent of the participants that participated in this study tolerated the product very very well meaning they tolerated jigsaw magnesium SRT exceptionally well just so that you know that is very very rare in a study you don't usually see something that well tolerated usually it's like a 70 80 % stick through rate most people end up falling off so not only do we find that it has amazing effects in the body we also found that it's well tolerated amongst most people and to add one more thing to make this really really powerful when you're normally looking at a clinical study usually you're looking at a one and a half times better than placebo effect well in this case five times better than placebo so most pharmaceutical companies when they're doing any kind of clinical trial all they are looking for is the drug to be one and a half times better than placebo and that it's kind of a gold standard well mag SRT five times better than placebo so as always make sure you're keeping it locked in here in my channel I did put a link down to jigsaw magnesium below you can get it on Amazon this isn't a hard core product push it's just to tell you about an amazing amazing thing and an awesome study that I've been a part of so link is down below but as always keep it locked in here in my channel want to see more magnesium content hit it in the comments below I'll help you understand how it works in the body


32 thoughts on “Magnesium Absorbency: Our Clinical Trial Results- Thomas DeLauer

  1. Looking for some advice. Just got back my Magnesium RBC test and it is showing 43.0 mg/g as the level. I do believe if you convert it to dL it would be 4.3mg/dL. Can someone tell me if that is a normal level or not?

  2. Great content as always, Thomas! And I would appreciate you speaking more slowly! Your videos are highly technical, and you talk SUPER fast sometimes; often much faster than my brain can follow.

  3. In your video – it was not clear on when you are supposed to be taking a magnesium supplement? Example: during the morning or during the day or night? Before meals or after meals? With meals? Also we talk about Magnesium in this video – but we don't talk about what complimenting nutrients to also take with our magnesium…such as Calcium or Vitamin D and/or K. There are so many supplements out there. I think we need a video on how to take nutritional supplements, when to take them and how to take them? I wish there was a chart or a visual diagram on the compatibility of nutritional supplements and a timeline schedule of when to be taking them drawn up. I wish that we could work together on this.

  4. Timeline (Bioavailability) of Magnesium Compounds in Hours: Which Magnesium Compound Works Best?

    Uysal N, et al. Biol Trace Elem Res. 2019.

    https://www.ncbi.nlm.nih.gov/m/pubmed/29679349/

  5. One study I read had magnesium oxide only absorb %2 less than citrate. The test included seven or so types of magnesium and the small difference in absorption doesn't warrant the insane price increase. Wish I could find the link.

  6. I've recently listened to your podcast with Ben Greenfield on Magnesium.

    I've purchased some DiMag Malate, but want to stack with creatine for a pre-workout.

    Can I Stack DiMag Malate with Creatine Monohydrate, or am I best going with a Creatine Malate?

    Thanks Thomas,
    Nathan.

  7. Im taking a mixed blend of Magnessium Taurate and Glycinate powder for my anxiety and it works just as good as taking a pharmaceutical drug.. Feel relaxed 20 mins after i take it, only bad thing it carries on to the next day abit and feel quite drowsey while im in work but i sopose its better than feeling anxious 24/7.

  8. I've been waking up with cramps in my feet and calves, potentially due to an electrolyte deficiency or due to peripheral neuropathy. My blood sugar is under control (A1C and personal meter) so I'm looking for more help. I've been drinking ACV, and that's not helping. I've also been taking magnesium glycinate and potassium for a few days, but nothing's changing. I was taking magnesium citrate, but it just gave me the runs. I've been taking magnesium oxide softgels for a long time, and they virtually ended my inflammation—all of it. Sadly, the neuropathy and/or cramps continue. I recently added benfotiamine, hoping that would help, and of course, I'm eating cruciferous and green leafies (which, of course, makes it more of a challenge to keep my glucose under control.) I'm really grasping at straws here. I'm hoping this helps. I'm also hoping the neuropathy isn't still progressing.and concerned about the possibility of peripheral arterial disease.

  9. There was one study done in New Zealand on epsom salt baths. It showed that taking a bath in epsom salt does increase serum levels of magnesium.

  10. I did lots of forms of magnesium therapy. Jigsaw's product was the best that I personally tried and I still take it to this day. Previously I took Doctor's Best chelated…but it did not compare to Jigsaw.

  11. The bases of any scientific study is how many times it can be repeated with the same results. Did this happen or is this just on one study's claims?

  12. I take Magnesium Chelated and Solgar Magnesium with Vitamin B-6 Tablets for my Irregular heart beat.

  13. hi for magnesium threonate should you take it with calcium to break it down? for memory and anxiety i see citrate and threonate as the two best.

  14. It would've been great if you had included the other types of magnesium (except citrate) in the study so we could have compared them to something other than placebo.

  15. Please make more vids on magnesium. I’ve been supplementing mag citrate and I feel like it works. My bowl movements are better and I do feel relaxed but I wanna make sure I’m taking the right form. Plus when is the best time to supplement it and how often. I’m guna continue to watch ur vids on magnesium because i know you have many but I wish you would make a video that explains everything g we need to know and how we should go about buying magnesium.

  16. Still trying to find the best solution. Citrate made the cramps worse because it dehydrated me (thus laxative effect). Switched to liquid Oxide doesn’t seem to offer a change. Wake up with cramps from calves down to my feet though not as bad. I have to jump out of bed and start walking around immediately. Need to refuel to fix the deficiency without adding to the dehydration. Solutions?

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